Anti-Hu IgE Biotin

EXBIO

Anti-Hu IgE Biotin

7

Flow cytometry: Recommended dilution: 1-12 microg/ml

Flow Cytometry, ELISA

Research Use Only

BE5

1 mg/ml

Biotin

IgG1

Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.

Human

2°C to 8°C

12352203