Anti Human SPHK1 Polyclonal

Applied Biological Materials

Anti Human SPHK1 Polyclonal

9

Western Blot, ELISA

Research Use Only

Polyclonal

1 ug/ul

Rabbit

IgG

The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Human, Mouse

-20°C,2°C to 8°C

12352203