ELISA of mouse immunoglobulins shows RM218 reacts to both mouse IgG3kappa and IgG3lambda; No cross reactivity with mouse IgG1, IgG2a, IgG2b, IgM, IgA, IgE, human IgG, or rat IgG. The plate was coated with 50 ng/well of different immunoglobulins. 200 ng/mL, 50 ng/m
ELISA of mouse immunoglobulins shows RM218 reacts to both mouse IgG3kappa and IgG3lambda; No cross reactivity with mouse IgG1, IgG2a, IgG2b, IgM, IgA, IgE, human IgG, or rat IgG. The plate was coated with 50 ng/well of different immunoglobulins. 200 ng/mL, 50 ng/m
anti-IgA (mouse), Rabbit Monoclonal (RM220) (Biotin)
REV-31-1099-02
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityMouse
Overview
- SupplierRevMAb Biosciences
- Product Nameanti-IgA (mouse), Rabbit Monoclonal (RM220) (Biotin)
- Delivery Days Customer5
- Antibody SpecificityThis antibody specifically reacts to mouse IgA. No cross reactivity with mouse IgG1, IgG2a, IgG2b, IgG2c, IgG3, IgM, IgE, or human IgA.
- ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRM220
- Concentration1 mg/ml
- ConjugateBiotin
- FormulationLiquid
- HostRabbit
- IsotypeIgG
- Protein IDP01878
- Protein NameIg alpha chain C region
- Scientific DescriptionImmunoglobulin A (IgA) is an antibody isotype that plays a crucial role in the immune function of mucous membranes. The IgA dimeric form is the most prevalent and is also called secretory IgA (sIgA). sIgA is the main immunoglobulin found in mucous secretions, including tears, saliva, sweat, colostrum and secretions from the genitourinary tract, gastrointestinal tract, prostate and respiratory epithelium. It is also found in small amounts in blood. The secretory component of sIgA protects the immunoglobulin from being degraded by proteolytic enzymes; thus, sIgA can survive in the harsh gastrointestinal tract environment and provide protection against microbes that multiply in body secretions. In the blood, IgA interacts with the Fc receptor called FcalphaRI (or CD89), which is expressed on immune effector cells, to initiate inflammatory reactions. - Recombinant Antibody. This antibody specifically reacts to mouse IgA. No cross reactivity with mouse IgG1, IgG2a, IgG2b, IgG2c, IgG3, IgM, IgE, or human IgA. Applications: WB (nonreduced), IP, ICC, IHC, FACS, ELISA . Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Immunoglobulin A (IgA) is an antibody isotype that plays a crucial role in the immune function of mucous membranes. The IgA dimeric form is the most prevalent and is also called secretory IgA (sIgA). sIgA is the main immunoglobulin found in mucous secretions, including tears, saliva, sweat, colostrum and secretions from the genitourinary tract, gastrointestinal tract, prostate and respiratory epithelium. It is also found in small amounts in blood. The secretory component of sIgA protects the immunoglobulin from being degraded by proteolytic enzymes; thus, sIgA can survive in the harsh gastrointestinal tract environment and provide protection against microbes that multiply in body secretions. In the blood, IgA interacts with the Fc receptor called FcalphaRI (or CD89), which is expressed on immune effector cells, to initiate inflammatory reactions.
- ReactivityMouse
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203