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anti-IgG4 Fc (human), Rabbit Monoclonal (RM217) (Biotin)

Research Use Only
REV-31-1100-02
RevMAb Biosciences
ApplicationsELISA, Flow Cytometry
Product group Antibodies
ReactivityHuman
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    RevMAb Biosciences
  • Product Name
    anti-IgG4 Fc (human), Rabbit Monoclonal (RM217) (Biotin)
  • Delivery Days Customer
    5
  • Applications
    ELISA, Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    RM217
  • Concentration
    1 mg/ml
  • Conjugate
    Biotin
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    IgG (Immunoglobulin G) is the most abundant Ig isotype in serum and makes up approximately 75% of all serum Immunoglobulins. In humans, there are four subclasses of IgG with highest serum concentrations of IgG1 followed by IgG2, IgG3 and IgG4. The IgG molecule consists of two heavy and two lights chains (kappa or lambda) resulting in a molecule with two arms for antigen binding. High levels of IgG antibodies are induced following the initial IgM response in a typical immune response to antigens. Because of its relative abundance and excellent specificity toward antigens, IgG is the principle antibody used in immunological research and clinical diagnostics. Clinically, measured IgG antibody levels are generally considered to be indicative of an individuals immune status to particular pathogens. This anti-human secondary antibody has well-characterized specificity for human IgG4 immunoglobulins Fc region and is useful in the detection, sorting or purification of its specified target. In general, secondary antibodies offer increased versatility enabling users to use many detection systems (e.g. HRP, AP, fluorescence). They can also provide greater sensitivity through signal amplification as multiple secondary antibodies can bind to a single primary antibody. - Recombinant Antibody. This antibody reacts to the Fc region of human IgG4. No cross reactivity with human IgG1, IgG2, IgG3, IgM, IgA, IgD, IgE, mouse IgG, rat IgG, or goat IgG. Applications: FACS, ELISA . Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. IgG (Immunoglobulin G) is the most abundant Ig isotype in serum and makes up approximately 75% of all serum Immunoglobulins. In humans, there are four subclasses of IgG with highest serum concentrations of IgG1 followed by IgG2, IgG3 and IgG4. The IgG molecule consists of two heavy and two lights chains (kappa or lambda) resulting in a molecule with two arms for antigen binding. High levels of IgG antibodies are induced following the initial IgM response in a typical immune response to antigens. Because of its relative abundance and excellent specificity toward antigens, IgG is the principle antibody used in immunological research and clinical diagnostics. Clinically, measured IgG antibody levels are generally considered to be indicative of an individuals immune status to particular pathogens. This anti-human secondary antibody has well-characterized specificity for human IgG4 immunoglobulins Fc region and is useful in the detection, sorting or purification of its specified target. In general, secondary antibodies offer increased versatility enabling users to use many detection systems (e.g. HRP, AP, fluorescence). They can also provide greater sensitivity through signal amplification as multiple secondary antibodies can bind to a single primary antibody.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203