Anti-IKK alpha Antibody [SN06-99]

HUABIO

Anti-IKK alpha Antibody [SN06-99]

7

Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P,FC,IP

Research Use Only

Monoclonal

SN06-99

1 mg/ml

Unconjugated

CHUK

component of inhibitor of nuclear factor kappa B kinase complex

BPS2, IKBKA, IKK-1, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16, inhibitor of nuclear factor kappa-B kinase subunit alpha, I-kappa-B kinase 1, I-kappa-B kinase-alpha, IKK-a kinase, IkB kinase alpha subunit, Nuclear factor NFkappaB inhibitor kinase alpha, conserved helix-loop-helix ubiquitous kinase, transcription factor 16

Rabbit

IgG

Inhibitor of nuclear factor kappa-B kinase subunit alpha

Inhibitor of nuclear factor kappa-B kinase subunit alpha (IKK-alpha) also known as IKK1 or conserved helix-loop-helix ubiquitous kinase (CHUK) is a protein kinase that in humans is encoded by the CHUK gene. IKK-alpha is part of the IkappaB kinase complex that plays an important role in regulating the NF-kappaB transcription factor. However, IKK-alpha has many additional cellular targets, and is thought to function independently of the NF-kappaB pathway to regulate epidermal differentiation. IKK-alpha is a member of the serine/threonine protein kinase family and forms a complex in the cell with IKK-beta and NEMO. IKK-alpha has been shown to function in epidermal differentiation independently of the NF-kappaB pathway. The zebrafish homolog of IKK-alpha has also been shown to play a role in the differentiation of the embryonic epithelium. IkappaB kinase alpha (IKKalpha) is a regulator of keratinocyte terminal differentiation and proliferation and plays a role in skin cancer.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161