Anti-IKZF3 Antibody [JE62-81]

HUABIO

Anti-IKZF3 Antibody [JE62-81]

2

Western Blot

Research Use Only

Monoclonal

JE62-81

1 mg/ml

Unconjugated

IKZF3

IKAROS family zinc finger 3

AIO, AIOLOS, IMD84, ZNFN1A3, zinc finger protein Aiolos, zinc finger DNA binding protein Aiolos, zinc finger protein, subfamily 1A, 3 (Aiolos)

Rabbit

IgG

Zinc finger protein Aiolos

Zinc finger protein Aiolos also known as Ikaros family zinc finger protein 3 is a protein that in humans is encoded by the IKZF3 gene. This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

-20°C,2°C to 8°C

41116161