Anti-IL-27p28 [MM27-7B1]

Absolute Antibody

Anti-IL-27p28 [MM27-7B1]

9

This antibody is specific for the IL-27 p28 subunit.

This antibody has been used to detect intracellular IL-27 in flow cytometric analysis (Bosmann et al, 2014), and to detect serum and cell culture supernatant IL-27 in sandwich ELISA analysis (Marillier et al, 2014). This antibody blocks IL-27, and is able to restore IL-9 and IL-17A production in the presence of IL-27 (Uyttenhove et al, 2011). Administration of this antibody blocks graft-versus-host disease upon B6 cell transfer to B6D2 recipient mice (Marillier et al, 2014).

Flow Cytometry, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

MM27-7B1

Il27

interleukin 27

Il; IL-; IL-27; IL-27 p28 subunit; IL-27 subunit alpha; IL-27-A; IL27-A; IL-27p28; Il30; interleukin 30; interleukin-27 subunit alpha; p2; p28

Rabbit

IgG

Interleukin-27 subunit alpha

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Mouse

-20°C,2°C to 8°C

12352203