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Western blot analysis using anti-IL-37 (human), pAb (Prod. No. AG-25A-0111) at 1:2.000 dilution:1. Recombinant human IL-37-His (50ng)2. Human IL-37-FLAG transfected HEK293 cell lysate(100microg)3. Human IL-37-tag free transfecte
Western blot analysis using anti-IL-37 (human), pAb (Prod. No. AG-25A-0111) at 1:2.000 dilution:1. Recombinant human IL-37-His (50ng)2. Human IL-37-FLAG transfected HEK293 cell lysate(100microg)3. Human IL-37-tag free transfecte
Western blot analysis using anti-IL-37 (human), pAb (Prod. No. AG-25A-0111) at 1:2.000 dilution:1. Recombinant human IL-37-His (50ng)2. Human IL-37-FLAG transfected HEK293 cell lysate(100microg)3. Human IL-37-tag free transfecte

anti-IL-37 (human), pAb

AG-25A-0111
AdipoGen Life Sciences
ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetIL37
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    anti-IL-37 (human), pAb
  • Delivery Days Customer
    10
  • Applications
    ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Gene ID27178
  • Target name
    IL37
  • Target description
    interleukin 37
  • Target synonyms
    FIL1; FIL1 zeta; FIL1(ZETA); FIL1Z; IL-1 zeta; IL1F7; IL-1F7; IL1F7 (canonical product IL-1F7b); IL-1F7b (IL-1H4, IL-1H, IL-1RP1); IL-1H; IL1H4; IL-1H4; IL1RP1; IL-1RP1; IL-1X protein; IL-23; IL-37; interleukin 1 family member 7; interleukin 1, zeta; interleukin-1 homolog 4; interleukin-1 superfamily z; interleukin-1-related protein; interleukin-23; interleukin-37
  • Host
    Rabbit
  • Protein IDQ9NZH6
  • Protein Name
    Interleukin-37
  • Scientific Description
    IL-37 (IL-1F7; IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor (IL-18R) and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide (LPS)-induced immunological reaction and LPS-induced osteoclast formation and bone resorption. - Polyclonal Antibody. Recognizes human IL-37. Detects a band of ~30kDa by Western blot. Source: Rabbit. Applications: ELISA, IHC, IP, WB. Liquid. 0.2microm-filtered solution in PBS, pH 7.4. Contains no preservatives. IL-37 (IL-1F7; IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor (IL-18R) and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide (LPS)-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203

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Figure 1. IHC analysis of IL37 using anti-IL37 antibody (A03607-3). IL37 was detected in paraffin-embedded section of human B lymphocytic tumor tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2microg/ml rabbit anti-IL37 Antibody (A03607-3) overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) (Catalog # SA1022) with DAB as the chromogen.
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