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ProductsBack/anti-IL-38, mAb (Nhat-1)
Mouse and human IL-38 is detected using anti-IL-38, mAb (Nhat-1) (AG-20B-0070).Method: Recombinant mouse IL-38 (AG-40B-0101) (lane 1), cell extracts from HEK 293 cells mock-transfected (lane 2) or transfected with human IL-38 (lane 3) were se
Mouse and human IL-38 is detected using anti-IL-38, mAb (Nhat-1) (AG-20B-0070).Method: Recombinant mouse IL-38 (AG-40B-0101) (lane 1), cell extracts from HEK 293 cells mock-transfected (lane 2) or transfected with human IL-38 (lane 3) were se
Mouse and human IL-38 is detected using anti-IL-38, mAb (Nhat-1) (AG-20B-0070).Method: Recombinant mouse IL-38 (AG-40B-0101) (lane 1), cell extracts from HEK 293 cells mock-transfected (lane 2) or transfected with human IL-38 (lane 3) were se

anti-IL-38, mAb (Nhat-1)

Research Use Only
AG-20B-0070
AdipoGen Life Sciences
ApplicationsWestern Blot, ELISA
DownloadMSDS
Product group Antibodies
ReactivityHuman, Mouse
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    anti-IL-38, mAb (Nhat-1)
  • Delivery Days Customer
    10
  • Antibody Specificity
    Recognizes human and mouse IL-38.
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    Nhat-1
  • Concentration
    1 mg/ml
  • Estimated Purity
    >95%
  • Formulation
    Liquid
  • Host
    Mouse
  • Isotype
    IgG2b
  • Scientific Description
    IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 as a IL-1 family receptor antagonist. Il-38 inhibits IL-36 signaling by binding to IL-1R6. IL-38 (aa 20-152) is released from apoptotic cells to limit inflammatory macrophage and downstream Th17 activation by blocking IL1RAPL1 (Interleukin-1 receptor accessory protein-like 1, TIGIRR-2) signaling. IL-38 is unregulated during some autoimmune diseases such as Systemic Lupus Erythematosus. - Monoclonal Antibody. Recognizes human and mouse IL-38. Isotype: Mouse IgG2bkappa. Clone: Nhat-1. Applications: ELISA, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 as a IL-1 family receptor antagonist. Il-38 inhibits IL-36 signaling by binding to IL-1R6. IL-38 (aa 20-152) is released from apoptotic cells to limit inflammatory macrophage and downstream Th17 activation by blocking IL1RAPL1 (Interleukin-1 receptor accessory protein-like 1, TIGIRR-2) signaling. IL-38 is unregulated during some autoimmune diseases such as Systemic Lupus Erythematosus.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203