Anti-IL-5 [2F2]

Absolute Antibody

Anti-IL-5 [2F2]

9

This antibody is specific for human rIL-5, and does not cross-react with human rIL-1alpha, rIL-lbeta, rIL-4, rIL-8, rM-CSF, or rTGF-alpha.

This antibody has been show to inhibit the binding of human rIL-5 to the alpha chain of the IL-5 receptor (Ames et al, 1995). This antibody inhibits the proliferation of murine B13 cells in response to human IL-5 (Ames et al, 1995).Neutralising antibodies against IL-5 represent a potential therapeutic strategy for the treatment of eosinophilia. The specificity of this antibody for human IL-5 has been confirmed in ELISA analysis (Ames et al, 1995).

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

2F2

Human

IgG1

Interleukin-5

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203