Anti-IL-9 [D9302C12]

Absolute Antibody

Anti-IL-9 [D9302C12]

7

In vitro, this antibody has inhibitory effects on IL-9 bioactivity, and inhibits the differentiation of Th17 cells and consequent production of IL-17 (Li et al, 2010). This antibody is also able to neutralise IL-9 in vivo (Li et al, 2010). Administration of this antibody suppresses acute experimental autoimmune encephalomyelitis (EAE), with an observed reduction in MOG-specific Th1 and Th17 cells in the periphery and the CNS (Li et al, 2010).

Flow Cytometry, Neutralisation/Blocking

blocking; FC

Research Use Only

Monoclonal

D9302C12

Il9

interleukin 9

Il-9, P40, interleukin-9, T-cell growth factor P40, cytokine P40

Mouse

IgG2a

Interleukin-9

This chimeric mouse antibody was made using the variable domain sequences of the original Hamster IgG2 format, for improved compatibility with existing reagents, assays and techniques.

Mouse

This antibody was raised by immunising Armenian hamsters with Baculovirus-expressed, recombinant murine IL-9.

-20°C,2°C to 8°C

12352203