Anti-IL23 (p19) [G23-8]

Absolute Antibody

Anti-IL23 (p19) [G23-8]

9

This antibody can neutralize the bioactivity of IL-23 with no effect on IL-12 p70 bioactivity. This antibody can be used for the detection of mouse IL-23 p19 in an ELISA (PMID: 18802055). This antibody was used in assay to determine the effect of anti-IL23p19 antibody on increase in IL-17 production after neutralization of IL-4 in T cells cultured with IL-4 DCs or with non transduced DCs (PMID: 17195211). This antibody was reported to inhibit lactic acid-induced enhancement of IL-17 production by OT-II mouse splenocytes that had been stimulated with the TLR ligand peptidoglycan (PGN) and bacillus Calmette-Guerin cell wall skeleton (BCG-CWS) (PMID: 18490716).

Functional Assay, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

G23-8

Il23a

interleukin 23, alpha subunit p19

IL-23, p19, interleukin-23 subunit alpha, IL-23 subunit alpha, IL-23-A, IL-23p19, interleukin-23 subunit p19

Mouse

IgG2a

Interleukin-23 subunit alpha

This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Mouse

-20°C,2°C to 8°C

41116161