Anti-IMPDH2 Rabbit mAb

PTM BIO

Anti-IMPDH2 Rabbit mAb

5

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

WB, ICC/IF, IP

Research Use Only

Monoclonal

11440

Unconjugated

Rabbit

IgG

Inosine-5'-monophosphate dehydrogenase 2

Inosine-5'-monophosphate dehydrogenase 2, also known as IMP dehydrogenase 2, is an enzyme that in humans is encoded by the IMPDH2 gene.IMP dehydrogenase 2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. IMPDH2 catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 has been identified as an intracellular target of the natural product sanglifehrin A.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse

Human, Mouse

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203