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Anti-inflammatory agent 35 [2293951-00-3]

HY-148552
MedChem Express
CAS Number2293951-00-3
Product group Chemicals
Estimated Purity99.77
Molecular Weight495.52
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Anti-inflammatory agent 35 [2293951-00-3]
  • Delivery Days Customer
    10
  • CAS Number
    2293951-00-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.77
  • Molecular Formula
    C27H29NO8
  • Molecular Weight
    495.52
  • Scientific Description
    Anti-inflammatory agent 35 (compound 5a27) is an orally active curcumin analogue with anti-inflammatory activity. Anti-inflammatory agent 35 blocks mitogen-activated protein kinase (MAPK) signaling and p65 nuclear translocation of NF-kB. Anti-inflammatory agent 35 also inhibits yellow neutrophil infiltration and pro-inflammatory cytokine production. Anti-inflammatory agent 35 significantly attenuates lipopolysaccharide (LPS)-induced acute lung injury (ALI) in vivo[1].
  • SMILES
    CC(OC1=CC=C(/C=C/C(N2C(/C(CCC2)=C/C3=CC(OC)=C(OC)C(OC)=C3)=O)=O)C=C1OC)=O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12131703

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