Anti-Interferon gamma Antibody [JM10-10]

HUABIO

Anti-Interferon gamma Antibody [JM10-10]

7

Flow Cytometry, Western Blot

WB,IHC-P,FC

Research Use Only

Monoclonal

JM10-10

1 mg/ml

Unconjugated

IFNG

interferon gamma

IFG, IFI, IMD69, interferon gamma, IFN-gamma, immune interferon

Rabbit

IgG

Interferon gamma

Interferon gamma (IFN-gamma) is a dimerized soluble cytokine that is the only member of the type II class of interferons. In humans, the IFN-gamma protein is encoded by the IFNG gene. IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral, some bacterial and protozoan infections. IFN-gamma is an important activator of macrophages and inducer of major histocompatibility complex class II molecule expression. Aberrant IFN-gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFN-gamma is produced predominantly by natural killer cells (NK) and natural killer T cells (NKT) as part of the innate immune response, and by CD4 Th1 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops as part of the adaptive immune response. IFN-gamma is also produced by non-cytotoxic innate lymphoid cells (ILC), a family of immune cells first discovered in the early 2010s.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161