Anti-JNK2 Antibody [SC05-85]

HUABIO

Anti-JNK2 Antibody [SC05-85]

7

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IHC-P,IP,FC

Research Use Only

Monoclonal

SC05-85

1 mg/ml

Unconjugated

MAPK9

mitogen-activated protein kinase 9

JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK, mitogen-activated protein kinase 9, Jun kinase, MAP kinase 9, MAPK 9, c-Jun N-terminal kinase 2, c-Jun kinase 2, stress-activated protein kinase 1a, stress-activated protein kinase JNK2

Rabbit

IgG

Mitogen-activated protein kinase 9

c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield 10 isoforms through alternative mRNA splicing, including JNK1alpha1, JNK1beta1, JNK2alpha1, JNK2beta1, and JNK3alpha1, which represent the p46 isoforms, and JNK1alpha2, JNK1beta2, JNK2alpha2, JNK2beta2, and JNK3beta2, which represent the p54 isoforms.JNKs coordinate cell responses to stress and influence regulation of cell growth and transformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun, and other signaling kinases, including MEKK1 and p38.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161