Anti-JunB Antibody [SD081-08]

HUABIO

Anti-JunB Antibody [SD081-08]

7

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P,IP

Research Use Only

Monoclonal

SD081-08

1 mg/ml

Unconjugated

JUNB

JunB proto-oncogene, AP-1 transcription factor subunit

AP-1, transcription factor JunB, activator protein 1, jun B proto-oncogene, transcription factor AP-1 subunit JunB, transcription factor jun-B

Rabbit

IgG

Transcription factor JunB

The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein along with c-Fos is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.

Human

Human

Mouse,Rat

-20°C,2°C to 8°C

41116161