Anti-KIF5B Antibody [JE64-16]

HUABIO

Anti-KIF5B Antibody [JE64-16]

2

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

JE64-16

1 mg/ml

Unconjugated

KIF5B

kinesin family member 5B

HEL-S-61, KINH, KNS, KNS1, UKHC, kinesin-1 heavy chain, conventional kinesin heavy chain, epididymis secretory protein Li 61, kinesin 1 (110-120kD), kinesin heavy chain, ubiquitous kinesin heavy chain

Rabbit

IgG

Kinesin-1 heavy chain

Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. Through binding with PLEKHM2 and ARL8B, directs lysosome movement toward microtubule plus ends. Involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells

-20°C,2°C to 8°C

41116161