Anti-Kv1.1 potassium channel Antibody [SN66-06]

HUABIO

Anti-Kv1.1 potassium channel Antibody [SN66-06]

7

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,IP

Research Use Only

Monoclonal

SN66-06

1 mg/ml

Unconjugated

KCNA1

potassium voltage-gated channel subfamily A member 1

AEMK, EA1, HBK1, HUK1, KV1.1, MBK1, MK1, RBK1, potassium voltage-gated channel subfamily A member 1, potassium channel, voltage gated shaker related subfamily A, member 1, potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia), voltage-gated K(+) channel HuKI, voltage-gated potassium channel HBK1, voltage-gated potassium channel subunit Kv1.1

Rabbit

IgG

Potassium voltage-gated channel subfamily A member 1

Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution, and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming -subunits (KValpha), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KVbeta subunits that modify the gating properties of the coexpressed KValpha subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1.1, KV1.2, KV1.4, KV1.5 and KV1.6) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.

Human, Rat

Human,Rat

Mouse

-20°C,2°C to 8°C

41116161