Anti-LAG-3 [22G3]

Absolute Antibody

Anti-LAG3 [22G3]

7

The antibody is specific for LAG3. Lymphocyte activation gene 3 protein is an inhibitory receptor on antigen activated T-cells. It delivers inhibitory signals upon binding to ligands, such as FGL1.

The antibody specifically detected LAG3 protein in Western blot analysis. The antibody and the commercial antibody EPR20261 were used to stain tonsillar granulocytes and granulocytes in the appendix. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 22G3 was higher than the commercial antibody. The antibody and the commercially available antibody E3 were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN113234159A).

Western Blot, ELISA, ImmunoHistoChemistry

IHC; WB; ELISA

Research Use Only

Monoclonal

22G3

LAG3

lymphocyte activating 3

CD223; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3

Human

IgG1

Lymphocyte activation gene 3 protein

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques.

Human

Human

The original antibody was generated by immunizing mice with recombinant LAG3 protein.

-20°C,2°C to 8°C

12352203