Anti-LAM [A1]

Absolute Antibody

Anti-LAM [A1]

7

This antibody binds lipoarabinomannan (LAM) of Mycobacterium tuberculosis. LAM is a glycolipid and a virulence factor, having a primary function of inactivating macrophages and scavenging oxidative radicals.

The binding specificity of this antibody to Mycobacterium tuberculosis lipoarabinomannan (LAM) was determined using ELISA. This antibody is the matched pair of clone A12 (Ab03327) for the detection of LAM in a sandwich ELISA. The colloidal gold-labeled version of this antibody pair was used in the development of a qualitative double antibody sandwich ELISA for the detection of LAM (CN113480659).

ELISA

ELISA

Research Use Only

Monoclonal

A1

lprG

lipoprotein LprG

P27; Rv1411c

Mouse

IgG1

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.

Bacteria

Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium marinum, Mycobacterium malmoense, Mycobacterium scrofulaceum, Mycobacterium simiae, Mycobacterium xenopi

The original antibody was isolated from an scFv phage display library generated from the peripheral blood lymphocytes of a healthy human subject. Later one the scFv wea converted to human IgG1.

-20°C,2°C to 8°C

12352203