Anti-LDL Receptor Rabbit mAb

PTM BIO

Anti-LDL Receptor Rabbit mAb

5

Flow Cytometry, Western Blot, ImmunoHistoChemistry Paraffin

WB, IHC-P, FC

Research Use Only

Monoclonal

JRMR-10562

Unconjugated

Rabbit

IgG

Low-density lipoprotein receptor

LDL receptor is a transmembrane protein, which binds LDL (low-density lipoprotein), the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. The complexes recycle through the endocytic pathway. Variants affecting this gene cause familial hypercholesterolemia, a disorder of lipoprotein metabolism characterized by elevated serum LDL cholesterol levels. Besides, LDLR also acts as a receptor for hepatitis C virus in hepatocytes and vesicular stomatitis virus.

Stable for 12 months from date of receipt/reconstitution.

Human

Human

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203