Anti-LMO4 Rabbit mAb

PTM BIO

Anti-LMO4 Rabbit mAb

5

Western Blot

WB

Research Use Only

Monoclonal

JMMR-3200

Unconjugated

Rabbit

IgG

LIM domain transcription factor LMO4

LMO4 is a LIM zinc-binding domain-containing protein. LMO4 cDNA was first isolated from a breast tumor cDNA library. This transcriptional modulator is overexpressed in several epithelial cancers such as prostate, pancreas, and breast. LMO4 exhibits pro-oncogenic activities by inducing centrosome amplification and mitotic spindle abnormalities. LMO4 is also expressed in the brain, in regions involved in learning and the regulation of motivated behavior. In the basolateral amygdala, LMO4 functions to negatively regulate fear learning. Furthermore, in the nucleus accumbens, LMO4 was found to regulate the behavioral effects of cocaine.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse

Human, Mouse

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203