ProductsBack/Anti-LRP1 Rabbit mAb

Anti-LRP1 Rabbit mAb

Name: Anti-LRP1 Rabbit mAb
SKU: PTM-6610_P78
Availability: BackOrder

PTM-6610

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse, Rat

Overview

Supplier
PTM BIO
Product Name
Anti-LRP1 Rabbit mAb
Delivery Days Customer
5
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin
Applications Supplier
WB, IHC-P, ICC/IF
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
JRMR-10840-23
Conjugate
Unconjugated
Host
Rabbit
Isotype
IgG
Protein IDQ07954
Protein Name
Prolow-density lipoprotein receptor-related protein 1
Scientific Description
LRP1 is a type I transmembrane receptor that mediates the endocytosis of various ligands. LRP1 plays important roles in lipid homeostasis, signaling transduction, embryonic development, and glucose metabolism. In addition, LRP1 regulates APP processing and facilitates the clearance of beta-amyloid. This finding makes LRP1 a potential therapeutic target for Alzheimer’s disease. LRP1 preprotein is proteolytically processed by furin to generate a 515 kDa extracellular alfa subunit and a membrane-anchored 85 kDa bèta subunit, which together form the mature receptor.
Shelf life instruction
Stable for 12 months from date of receipt/reconstitution.
Reactivity
Human, Mouse, Rat
Reactivity Supplier
Human, Mouse, Rat
Reactivity Supplier Note
Protein A purified
Storage Instruction
Store at -20°C. Avoid freeze/thaw cycles.
UNSPSC
12352203