anti-LTbetaR (human), mAb (ANCLTR2/9E2) (preservative free)
ANC-267-820
ApplicationsFlow Cytometry, ELISA
Product group Antibodies
ReactivityHuman
Overview
- SupplierAncell Corporation
- Product Nameanti-LTbetaR (human), mAb (ANCLTR2/9E2) (preservative free)
- Delivery Days Customer10
- ApplicationsFlow Cytometry, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDANCLTR2/9E2
- HostMouse
- IsotypeIgG1
- Scientific DescriptionMonoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANCLTR2/9E2. Applications: ELISA, FACS. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival. - The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203