Anti-MAC-1 [YBM15.1]

Absolute Antibody

Anti-MAC-1 [YBM15.1]

9

This antibody recognizes murine integrine MAC-1 (Itgam/Cd11b). This integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens.

This antibody is recommended for the detection and analysis of MAC-1, the murine equivalent of CD11b. For instance, YBM15.1 was used in a panel of antibodies in the assessment of the presence of antigenic determinants on normal erythroid progenitors via flow cytometry (Watt et al., 1987; pmid: 3330997). This antibody was used to detect the integrin MAC-1 in the neural tissue of Biozzi ABH mice infected with Semliki Forest virus (SFV) A7(74) via immunohistochemistry (Smith et al., 2000; pmid: 10814783).

Flow Cytometry, ImmunoHistoChemistry

Research Use Only

Monoclonal

YBM15.1

Rat

IgG2b

Integrin alpha-M

Mouse

-20°C,2°C to 8°C

12352203