Anti-Machupo virus GP1 [MAC1], Human IgG1, kappa

Absolute Antibody

Anti-Machupo virus GP1 [MAC1], Human IgG1, kappa

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This antibody binds the TfR1 binding site in the glycoprotein GP1 of Machupo virus (MACV), which belongs to genus Mammarenavirus, family Arenaviridae. New World (NW) hemorrhagic fever (HF) arenaviruses are a group of rodent-borne zoonotic pathogens that c

This antibody is highly specific for binding to Machupo virus and does not cross react with Junin virus. This antibody is capable of binding MACV in an ELISA. This antibody neutralized HIV-1-based virus particles, pseudotyped with full-length MACV GP and rLCMV/MACV-GP chimeric viruses in an in vitro neutralization assay with an IC50 of 0.004 microg/mL and 13.0 microg/mL respectively (PMID: 35315691).

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

MAC1

Human

IgG1

Pre-glycoprotein polyprotein GP complex

Virus

-20°C,2°C to 8°C

12352203