Anti-MADH7/SMAD7 Rabbit mAb
PTM-6221
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
Overview
- SupplierPTM BIO
- Product NameAnti-MADH7/SMAD7 Rabbit mAb
- Delivery Days Customer5
- ApplicationsWestern Blot
- Applications SupplierWB
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDJRMR-10616-57
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Protein IDO15105
- Protein NameMothers against decapentaplegic homolog 7
- Scientific DescriptionThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3).
- Shelf life instructionStable for 12 months from date of receipt/reconstitution.
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteProtein A purified
- Storage InstructionStore at -20°C. Avoid freeze/thaw cycles.
- UNSPSC12352203