Anti-MAP-2 [AA5 (AP18)]

Absolute Antibody

Anti-MAP-2 [AA5 (AP18)]

7

This antibody is specific to the phosphorylated form of MAP2a, b, c and shows no cross-reactivity with other MAPs, tau or tubulin. This antibody reacts with dendrites and cell bodies of neurons. It is useful in studies of neuron structure in normal and ma

While testing the specificity of the mouse version of this antibody, a western blot on P9 quail and adult rat brain was performed using the mouse version of this antibody. Furthermore, quail cerebellum was immunologically stained using the mouse version of this antibody (Tucker et al, 1988; pmid:3199190). To examine the relationship between changes in tau phosphorylation and loss of MAP2 immunmoreactivity, immunocytochemistry was performed (Ashford et al, 1998; pmid:9786247). While assessing experience-dependent modifications in MAP2 phosphorylation in rat olfactory bulb. a western blot was performed against adult rat olfactory bulb proteins using the mouse version of this antibody. Furthermore, immunohistochemistry was performed against coronal sections of olfactory bulbs using the mouse version of this antibody (Philpot et al, 1997; pmid:9391014). While studying subependymal giant cell astrocytoma, immunohistochemistry was preformed using the mouse version of this antibody (Lopes et al, 1995; pmid:8928613).

Western Blot, ImmunoHistoChemistry

WB; IHC

Research Use Only

Monoclonal

AA5 (AP18)

Human

IgG1

Methionine aminopeptidase 2

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Avian, Bovine, Human, Rat, Xenopus

Birds, Cow, Clawed frog, Human, Rat

The mouse version of this antibody was generated by immunizing mice with taxol-stabalized microtubules from rat brain.

-20°C,2°C to 8°C

12352203