Anti-Marburg virus nucleoprotein [sdAb 4]

Absolute Antibody

Anti-Marburg virus nucleoprotein [sdAb 4]

9

sdAb B is specific for MARV-Mus, -Rav, and -Ang strains of the MARV virus but shows no cross-reactivity with representative strains of the 4 EBOV species. The antibody recognises NP, a critical viral structural protein that envelopes the RNA genome.

ELISA was used to establish the specificity of sdAb B for MARV virus strains (Sherwood et al, 2007). sdAb has been crystallised with its antigen NP (Garza et al, 2017). Cross-linking dimeric sdAb to NP restricted viral packaging (Darling et al, 2017).

ELISA, Other Application

Research Use Only

Monoclonal

sdAb 4

Mouse

IgG1

This chimeric mouse antibody was made using a variable domain sequence of the original VHH format, for improved compatibility with existing reagents, assays and techniques.

Virus

-20°C,2°C to 8°C

12352203