Anti-M-CSF Antibody [SU0413]

HUABIO

Anti-M-CSF Antibody [SU0413]

7

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,IF-Cell,IP

Research Use Only

Monoclonal

SU0413

1 mg/ml

Unconjugated

CSF1

colony stimulating factor 1

CSF-1, MCSF, PG-M-CSF, macrophage colony-stimulating factor 1, CSF1-hERV-LTR71B fusion protein, colony stimulating factor 1 (macrophage), lanimostim, macrophage colony stimulating factor 1, proteoglycan macrophage colony-stimulating factor

Rabbit

IgG

Macrophage colony-stimulating factor 1

The macrophage colony-stimulating factor (M-CSF), also designated CSF-1, was originally discovered in serum, urine and other biological fluids as a factor that can stimulate the formation of macrophage colonies from bone marrow hematopoietic progenitor cells. M-CSF is a homodimeric cytokine that is produced by fibroblasts, epithelial cells, bone marrow stromal cells, osteoblasts, keratinocytes, macrophages, T cells and B cells. M-CSF is a glycoprotein required for the proliferation and differentiation of mononuclear phagocytes, including osteoclasts. M-CSF has also been identified as an important mediator of the inflammatory response and can regulate the release of proinflammatory cytokines from macrophages. M-CSF exerts its pleiotropic effects by binding to a single type of high affinity cell surface receptor that is encoded by the c-Fms proto-oncogene.

Human, Mouse

Human,Mouse

-20°C,2°C to 8°C

41116161