Anti-MEF2A Antibody [JA33-04]

HUABIO

Anti-MEF2A Antibody [JA33-04]

7

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P

Research Use Only

Monoclonal

JA33-04

1 mg/ml

Unconjugated

MEF2A

myocyte enhancer factor 2A

ADCAD1, RSRFC4, RSRFC9, mef2, myocyte-specific enhancer factor 2A, MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A), serum response factor-like protein 1

Rabbit

IgG

Myocyte-specific enhancer factor 2A

Transcriptional activator which binds specifically to the MEF2 element, 5-YTA[AT]4TAR-3, found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161