Anti-MEK3+MEK6 Antibody [JJ087-09]

HUABIO

Anti-MEK3+MEK6 Antibody [JJ087-09]

7

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P,FC,IP

Research Use Only

Monoclonal

JJ087-09

1 mg/ml

Unconjugated

MAP2K3

mitogen-activated protein kinase kinase 3

MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2, dual specificity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, MAPK/ERK kinase 3, MAPKK 3, MEK 3, SAPK kinase 2, stress-activated protein kinase kinase 2

Rabbit

IgG

Dual specificity mitogen-activated protein kinase kinase 3

A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161