Anti-MEK5 Antibody [SD208-6]

HUABIO

Anti-MEK5 Antibody [SD208-6]

7

ImmunoFluorescence, Western Blot

WB,IF-Cell,IF-Tissue

Research Use Only

Monoclonal

SD208-6

1 mg/ml

Unconjugated

MAP2K5

mitogen-activated protein kinase kinase 5

HsT17454, MAPKK5, MEK5, PRKMK5, dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAP kinase kinase MEK5b, MAPK/ERK kinase 5, MAPKK 5, MEK 5

Rabbit

IgG

Dual specificity mitogen-activated protein kinase kinase 5

A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

Human

Human

-20°C,2°C to 8°C

41116161