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Anti-Mesothelin CAR Lentivirus (P4 ScFv-CD8-4-1BB-CD3aeta)

Anti-Mesothelin CAR Lentivirus (P4 ScFv-CD8-4-1BB-CD3aeta)

Research Use Only
78703
BPS Bioscience
Product group Molecular Biology
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    Anti-Mesothelin CAR Lentivirus (P4 ScFv-CD8-4-1BB-CD3aeta)
  • Delivery Days Customer
    7
  • Applications
    Other Application
  • Certification
    Research Use Only
  • Scientific Description
    The Anti-mesothelin CAR lentiviruses are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles that are ready to infect almost all types of mammalian cells, including primary and non-dividing cells. These viruses transduce the ScFv (single-chain fragment variable) of anti-mesothelin (Clone P4) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3aeta signaling domains. A B Figure 1. (A) Schematic of the lenti-vector used to generate the anti-mesothelin CAR lentivirus and (B) Construct diagram showing components of the anti-mesothelin CAR.
  • Storage Instruction
    -80°C
  • UNSPSC
    41106621

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