The expression of anti-Mesothelin CAR in HEK293 cells transduced with anti-mesothelin CAR lentivirus
The expression of anti-Mesothelin CAR in HEK293 cells transduced with anti-mesothelin CAR lentivirus
Anti-Mesothelin CAR Lentivirus (P4 ScFv-CD8-4-1BB-CD3aeta)
78703
Product group Molecular Biology
Overview
- SupplierBPS Bioscience
- Product NameAnti-Mesothelin CAR Lentivirus (P4 ScFv-CD8-4-1BB-CD3aeta)
- Delivery Days Customer7
- ApplicationsOther Application
- CertificationResearch Use Only
- Gene ID10232
- Target nameMSLN
- Target descriptionmesothelin
- Target synonymsMPF, SMRP, mesothelin, CAK1 antigen, megakaryocyte potentiating factor, pre-pro-megakaryocyte-potentiating factor, soluble MPF mesothelin related protein
- Hazard Informationun3373
- Protein IDQ13421
- Protein NameMesothelin
- Scientific DescriptionThe Anti-mesothelin CAR lentiviruses are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles that are ready to infect almost all types of mammalian cells, including primary and non-dividing cells. These viruses transduce the ScFv (single-chain fragment variable) of anti-mesothelin (Clone P4) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3aeta signaling domains. A B Figure 1. (A) Schematic of the lenti-vector used to generate the anti-mesothelin CAR lentivirus and (B) Construct diagram showing components of the anti-mesothelin CAR.
- Storage Instruction-80°C
- UNSPSC41115812
- SpeciesHuman
