Anti-Methylmalonyl Coenzyme A mutase Antibody [JE62-36]

HUABIO

Anti-Methylmalonyl Coenzyme A mutase Antibody [JE62-36]

2

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

JE62-36

1 mg/ml

Unconjugated

MMUT

methylmalonyl-CoA mutase

MCM, MUT, methylmalonyl-CoA mutase, mitochondrial, methylmalonyl Coenzyme A mutase, methylmalonyl-CoA isomerase, methylmalonyl-CoA mutase c.*192delA, methylmalonyl-CoA mutase c.*51C>G, methylmalonyl-CoA mutase variant c.1495G>A, methylmalonyl-CoA mutase variant c.2011A>G, methylmalonyl-CoA mutase variant c.2150G>T, methylmalonyl-CoA mutase variant c.322C>T, methylmalonyl-CoA mutase variant c.613_615delGAA, methylmalonyl-CoA mutase variant c.636G>A, methylmalonyl-CoA mutase variant c.643G>A, mutant methylmalonyl CoA mutase

Rabbit

IgG

Methylmalonyl-CoA mutase, mitochondrial

Methylmalonyl-CoA mutase (MCM), mitochondrial, also known as methylmalonyl-CoA isomerase, is a protein that in humans is encoded by the MUT gene. This vitamin B12-dependent enzyme catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA in humans. Mutations in MUT gene may lead to various types of methylmalonic aciduria. A deficiency of this enzyme is responsible for an inherited disorder of metabolism, methylmalonyl-CoA mutase deficiency, which is one of the causes of methylmalonic acidemia (also referred to as methylmalonic aciduria or MMA). Either mutations to the gene MUT (encodes methylmalonyl-CoA mutase), or MMAA (encodes a chaperone protein of methylmalonyl-CoA mutase, MMAA protein) can lead to methylmalonyl acidemia. Methylmalonyl-CoA mutase is expressed in high concentrations in the kidney, in intermediate concentrations in the heart, ovaries, brain, muscle, and liver, and in low concentrations in the spleen.

-20°C,2°C to 8°C

41116161