Anti-Mitofusin 2 Antibody [JE59-66]
HA720073
ApplicationsWestern Blot
Product group Antibodies
TargetMFN2
Overview
- SupplierHUABIO
- Product NameAnti-Mitofusin 2 Antibody [JE59-66]
- Delivery Days Customer2
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDJE59-66
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9927
- Target nameMFN2
- Target descriptionmitofusin 2
- Target synonymsCMT2A, CMT2A2, CMT2A2A, CMT2A2B, CPRP1, HMSN6A, HSG, MARF, MSL, mitofusin-2, hyperplasia suppressor, mitochondrial assembly regulatory factor, transmembrane GTPase MFN2
- HostRabbit
- IsotypeIgG
- Protein IDO95140
- Protein NameMitofusin-2
- Scientific DescriptionMitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains. Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PRKN recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161