Anti-Mouse CD127 Monoclonal Antibody(APC Conjugated)

Elabscience

Anti-Mouse CD127 Monoclonal Antibody(APC Conjugated)

12

Research Use Only

CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor alpha chain or IL-7Ralpha. It forms a heterodimer with the common gamma chain (gammac or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

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