Anti-mouse TIM-3 (CD366)-InVivo

Selleck Chemicals

Anti-mouse TIM-3 (CD366)-InVivo

9

Research Use Only

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Anti-mouse TIM-3 (CD366)-InVivo monoclonal antibody reacts with mouse TIM-3 (T cell immunoglobulin and mucin domain-3) also known as CD366. TIM-3 is specifically expressed at high levels on the surface of Th1 lymphocytes. This B8.2C12 antibody binds to the BALB/c allele of TIM-3 while reactivity to the C57Bl/6 allele. Inhibition of TIM-3 signaling in mice exacerbates experimental autoimmune encephalomyelitis and promotes IFNgamma production and Th1 cell proliferation.

2°C to 8°C

12352203