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Anti-Mouse/Human CD11b Monoclonal Antibody(PercP Conjugated)

Anti-Mouse/Human CD11b Monoclonal Antibody(PercP Conjugated)

E-AB-F1081F
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    Anti-Mouse/Human CD11b Monoclonal Antibody(PercP Conjugated)
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    CD11b is a 170 kD glycoprotein also known as alphaM integrin, Mac-1 alpha subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (beta2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
  • UNSPSC
    12352203

References

  • Wang Y, Zhang W, Xu Y, et al. Extracellular HMGB1 Impairs Macrophage-Mediated Efferocytosis by Suppressing the Rab43-Controlled Cell Surface Transport of CD91. Front Immunol. 2022,13:767630. doi: 10.3389/fimmu.2022.767630
    Read this paper

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