Anti-MPXV A35 protein [MV129], Mouse IgG2b, Fc Silent(tm), lambda

Absolute Antibody

Anti-MPXV A35 protein [MV129], Mouse IgG2b, Fc Silent(tm), lambda

9

This antibody strongly reacted with MPXV A35 protein in an ELISA assay at half-maximal effective concentrations (EC50) of 0.035 microg/mL. The binding affinity of the original human IgG1 version for MPXV A35 protein was determined using BLI and was reported to be Kd = 2.19 pM. In an in vitro virus neutralization assay, this antibody exhibited a strong neutralizing activity, with an IC50 of 2.68 microg/mL. This antibody was capable of recognizing MPXV A35 protein from convalescent serum samples in a western blot (PMID: 39002567).

Western Blot, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

MV129

Mouse

IgG2b

This is a reformatted mouse IgG2b Fc Silent™ antibody, based on the original mouse IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Virus

-20°C,2°C to 8°C

12352203