Anti-Myoglobin Antibody [A4B7]

HUABIO

Anti-Myoglobin Antibody [A4B7]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,IF-Tissue

Research Use Only

Monoclonal

A4B7

2 mg/ml

Unconjugated

MB

myoglobin

MYOSB, PVALB, myoglobin, nitrite reductase MB, pseudoperoxidase MB

Mouse

IgG1

Myoglobin

Myoglobin (symbol Mb or MB) is an iron- and oxygen-binding protein found in the cardiac and skeletal muscle tissue of vertebrates in general and in almost all mammals. Myoglobin is distantly related to hemoglobin. Compared to hemoglobin, myoglobin has a higher affinity for oxygen and does not have cooperative binding with oxygen like hemoglobin does. In humans, myoglobin is only found in the bloodstream after muscle injury. High concentrations of myoglobin in muscle cells allow organisms to hold their breath for a longer period of time. Myoglobin was the first protein to have its three-dimensional structure revealed by X-ray crystallography. Despite being one of the most studied proteins in biology, its physiological function is not yet conclusively established: mice genetically engineered to lack myoglobin can be viable and fertile, but show many cellular and physiological adaptations to overcome the loss. In humans, myoglobin is encoded by the MB gene. Myoglobin can take the forms oxymyoglobin (MbO2), carboxymyoglobin (MbCO), and metmyoglobin (met-Mb), analogously to hemoglobin taking the forms oxyhemoglobin (HbO2), carboxyhemoglobin (HbCO), and methemoglobin (met-Hb).

Human, Rat

Human,Rat

-20°C,2°C to 8°C

41116161