Anti-Myosin [11C6-E3]

Absolute Antibody

Anti-Myosin [11C6-E3]

9

This antibody is specific for MF1, a fragment spanning amino acids 1 - 562 in the S1 domain of the head region of murine cardiac myosin. This antibody cross-reacts with keratin and GlcNAc-BSA.

The reactivity of this antibody with mouse cardiac myosin and GlcNAc-BSA has been confirmed in ELISA analysis (Malkiel et al, 2000). The affinity of this antibody for myosin is higher than its affinity for GlcNAc-BSA (Malkiel et al, 2000).Administration of this antibody induces autoimmune myocarditis in DBA/2 mice, but not BALB/c mice (Liao et al, 1995). Equally, in immunohistochemical analysis, this antibody has been shown to be deposited throughout the hearts of DBA/2 mice, but not BALB/c mice (Liao et al, 1995).

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

11C6-E3

Mouse

IgG2b

Mouse

-20°C,2°C to 8°C

12352203