Anti-Myosin [2D6-B1]

Absolute Antibody

Anti-Myosin [2D6-B1]

7

This antibody is specific for MF1, a fragment spanning amino acids 1 - 562 in the S1 domain of the head region of murine cardiac myosin. This antibody cross-reacts with keratin and GlcNAc-BSA.

The reactivity of this antibody with mouse cardiac myosin and GlcNAc-BSA has been confirmed in ELISA analysis (Malkiel et al, 2000).The affinity of this antibody for myosin is higher than its affinity for GlcNAc-BSA (Malkiel et al, 2000). Administration of this antibody induces autoimmune myocarditis in DBA/2 mice, but not BALB/c mice (Liao et al, 1995). Equally, in immunohistochemical analysis, this antibody has been shown to be deposited throughout the hearts of DBA/2 mice, but not BALB/c mice (Liao et al, 1995).

Western Blot, ELISA, ImmunoHistoChemistry

ELISA; IHC; WB

Research Use Only

Monoclonal

2D6-B1

Mouse

IgG2a

Mouse

Mouse

This antibody was raised by immunising DBA/2 mice with cardiac myosin purified from BALB/c mouse hearts.

-20°C,2°C to 8°C

12352203