Anti-N9 Neuraminidase [NC41 ]

Absolute Antibody

Anti-N9 Neuraminidase [NC41 ]

9

This antibody is specific for the neuraminidase antigen of subtype N9, which also possesses HA activity. It cross-reacts with both avian and whale influenza. NC41 epitope is dominated by a few high-energy interactions.

A Fab fragment derived from this antibody by papain digestion has been used in X-ray diffusion analysis to crystallise N9 neuraminidase from avian influenza virus (Laver et al, 1987;Tulip et al, 1992) and whale avial-like virus (Tulip et al, 1992). In neuraminidase inhibition assays, this antibody has been shown to suppress the yield of virus from infected cells (Colman et al, 1987)

Other Application

Research Use Only

Monoclonal

NC41

Human

IgG1

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Virus

-20°C,2°C to 8°C

12352203