Anti-Nanog Antibody [SC05-70]

HUABIO

Anti-Nanog Antibody [SC05-70]

7

Flow Cytometry, ImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,FC,IHC-P

Research Use Only

Monoclonal

SC05-70

1 mg/ml

Unconjugated

Nanog

Nanog homeobox

2410002E02Rik, ENK, Stm1, ecat4, homeobox protein NANOG, ES cell-associated protein 4, early embryo specific expression NK family, early embryo specific expression NK-type homeobox protein, homeobox transcription factor Nanog

Rabbit

IgG

Homeobox protein NANOG

Nanog (from Tir Na Nog, the mythologic Celtic land of the ever young) is a divergent homeodomain protein that directs pluripotency and differentiation of undifferentiated embryonic stem cells. Nanog mRNA is present in pluripotent mouse and human cell lines and absent from differentiated cells. Human Nanog protein shares 52% overall amino acid identity with the mouse protein and 85% identity in the homeodomain. Human Nanog maps to gene locus 12p13.31, whereas mouse Nanog maps to gene loci 6 F2. Murine embryonic Nanog expression is detected in the inner cell mass of the blastocyst. High levels of human Nanog expression have been detected by Northern analysis in the undifferentiated NTERA-2 cl.D1 embryonal carcinoma cell line.

Human, Mouse

Human,Mouse

-20°C,2°C to 8°C

41116161