Bio-Connect
Schematic antibody structure of the recombinant antibody anti-Netrin-1 (human), mAb (rec.) (blocking) (2F5) (Prod. No. AG-27B-0018PF). The single chain variable human fragment (ScFv) selected by antibody phage display technology and specific to the antige
Schematic antibody structure of the recombinant antibody anti-Netrin-1 (human), mAb (rec.) (blocking) (2F5) (Prod. No. AG-27B-0018PF). The single chain variable human fragment (ScFv) selected by antibody phage display technology and specific to the antige
Schematic antibody structure of the recombinant antibody anti-Netrin-1 (human), mAb (rec.) (blocking) (2F5) (Prod. No. AG-27B-0018PF). The single chain variable human fragment (ScFv) selected by antibody phage display technology and specific to the antige

anti-Netrin-1 (human), mAb (rec.) (blocking) (2F5) (preservative free)

AG-27B-0018PF
AdipoGen Life Sciences
TargetNTN1
Product group Antibodies
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    anti-Netrin-1 (human), mAb (rec.) (blocking) (2F5) (preservative free)
  • Delivery Days Customer
    10
  • Antibody Specificity
    Recognizes human and mouse Netrin-1. Does not recognize Netrin-4. Blocks human and mouse Netrin-1 activity on tumor cell lines in vitro and in vivo. Inhibits Netrin-1-enhanced infectivity of Hepatitis C Virus particles.
  • Clone ID
    2F5
  • Concentration
    1 mg/ml
  • Estimated Purity
    >95%
  • Formulation
    Liquid
  • Gene ID9423
  • Target name
    NTN1
  • Target description
    netrin 1
  • Target synonyms
    epididymis tissue protein Li 131P; MRMV4; netrin 1, mouse, homolog of; netrin-1; NTN1L
  • Protein IDO95631
  • Protein Name
    Netrin-1
  • Scientific Description
    Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also involved in tumorigenesis by regulating apoptosis. Netrin-1 promotes atherosclerosis by retaining macrophages in the artery wall. Netrin-1 also governs induced pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by limiting apoptosis mediated by Netrin-1 receptors DCC or UNC5b. - Recombinant Antibody. Recognizes human and mouse Netrin-1. Does not recognize Netrin-4. Blocks human and mouse Netrin-1 activity on tumor cell lines in vitro and in vivo. Inhibits Netrin-1-enhanced infectivity of Hepatitis C Virus particles. Species cross-reactivity: Human, Mouse. Clone: 2F5. Isotype: Human IgG2lambda. Applications: ELISA, FUNC (Blocking). Host: HEK 293 cells. Liquid. In PBS containing 10% glycerol. Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also involved in tumorigenesis by regulating apoptosis. Netrin-1 promotes atherosclerosis by retaining macrophages in the artery wall. Netrin-1 also governs induced pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by limiting apoptosis mediated by Netrin-1 receptors DCC or UNC5b.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203

Related products

Product group Antibodies
AdipoGen Life Sciences
TargetLAG3
  • SizePrice
Product group Antibodies
AdipoGen Life Sciences
TargetLAG3
  • SizePrice
Detection of endogenous human LAG-3 by FACS analysis using anti-LAG-3 (human), mAb (17B4) (ATTO 647) (Prod. No. AG-20B-0012TS). Human PBMC were stimulated (B) or not (A) with 1microg/ml of superantigen SEB. After 2 days PBMC were stained with 10microg
Product group Antibodies
AdipoGen Life Sciences
TargetLAG3
  • SizePrice
Product group Antibodies
AdipoGen Life Sciences
TargetIFIH1
  • SizePrice
Detection of endogenous human BAFF-R with anti-BAFF-R (human), mAb (HuBR9.1) (AG-20B-0016). BJAB and Jurkat cells were stained with A) 20 microg /ml (and 2-fold dilutions) and B) 2microg /ml of anti-BAFF-R (human), mAb (HuBR9.1) in 50 microl FACS buffe
Product group Antibodies
AdipoGen Life Sciences
TargetTNFRSF13C
  • SizePrice
Detection of endogenous human BAFF-R with anti-BAFF-R (human), mAb (HuBR9.1) (AG-20B-0016). BJAB and Jurkat cells were stained with A) 20 microg /ml (and 2-fold dilutions) and B) 2microg /ml of anti-BAFF-R (human), mAb (HuBR9.1) in 50 microl FACS buffe
Product group Antibodies
AdipoGen Life Sciences
TargetTNFRSF13C
  • SizePrice
Product group Antibodies
AdipoGen Life Sciences
TargetTNFSF13B
  • SizePrice
Product group Antibodies
AdipoGen Life Sciences
TargetTNFRSF10A
  • SizePrice
Product group Antibodies
AdipoGen Life Sciences
TargetTNFRSF10A
  • SizePrice
Product group Antibodies
AdipoGen Life Sciences
TargetTNFRSF10A
  • SizePrice