Anti-Neurofilament light [MS-C2]
Ab00946-10.0
ApplicationsELISA
Product group Antibodies
Overview
- SupplierAbsolute Antibody
- Product NameAnti-Neurofilament light [MS-C2]
- Delivery Days Customer7
- Application Supplier NoteThe original human IgG1 version of the recombinant antibody MS-C2 was constructed in order to explore the antigen specificity of the Multiple Sclerosis B cell response (Willis et al, 2015; pmid: 26648933). The antibody was shown to bind two important neural antigens: neurofilament light (NF-L; strong binding with absorbance values that exceeded the mean +2SD of the control data set) and protocadherin PCDHGC3 (Willis et al, 2015; pmid: 26648933). Protocadherin gamma subfamily C, three (PCDHGC3) transcript variant three was of particular interest as a candidate autoantigen as protocadherin isoforms are predominantly expressed in the nervous system and have been implicated in human neurological disorders.
- ApplicationsELISA
- Applications SupplierELISA
- CertificationResearch Use Only
- Protein IDP07196
- Protein NameNeurofilament light polypeptide
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203