Bio-Connect

Anti-Neurofilament light [MS-C2]

Ab00946-10.0
Absolute Antibody
ApplicationsELISA
Product group Antibodies
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-Neurofilament light [MS-C2]
  • Delivery Days Customer
    7
  • Application Supplier Note
    The original human IgG1 version of the recombinant antibody MS-C2 was constructed in order to explore the antigen specificity of the Multiple Sclerosis B cell response (Willis et al, 2015; pmid: 26648933). The antibody was shown to bind two important neural antigens: neurofilament light (NF-L; strong binding with absorbance values that exceeded the mean +2SD of the control data set) and protocadherin PCDHGC3 (Willis et al, 2015; pmid: 26648933). Protocadherin gamma subfamily C, three (PCDHGC3) transcript variant three was of particular interest as a candidate autoantigen as protocadherin isoforms are predominantly expressed in the nervous system and have been implicated in human neurological disorders.
  • Applications
    ELISA
  • Applications Supplier
    ELISA
  • Certification
    Research Use Only
  • Protein IDP07196
  • Protein Name
    Neurofilament light polypeptide
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203