Anti-NF-kB p65 Mouse mAb

PTM BIO

Anti-NF-kB p65 Mouse mAb

5

Western Blot

WB

Antibody

Research Use Only

Monoclonal

12424

Unconjugated

Mouse

IgG

Transcription factor p65

Transcription factor p65 also known as nuclear factor NF-kappa-B p65 subunit is a protein that in humans is encoded by the RELA gene. RELA, also known as p65, is a REL-associated protein involved in NF-kappaB heterodimer formation, nuclear translocation and activation. NF-kappaB is an essential transcription factor complex involved in all types of cellular processes, including cellular metabolism, chemotaxis, etc. Phosphorylatedrylation and acetylation of RELA are crucial post-translational modifications required for NF-kappaB activation. RELA has also been shown to modulate immune responses, and activation of RELA is positively associated with multiple types of cancer.

Stable for 12 months from date of receipt/reconstitution.

Human

Protein G purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203