Anti-NFIB / NF1B2 Antibody [1H1]

HUABIO

Anti-NFIB / NF1B2 Antibody [1H1]

7

Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

IHC-P,FC

Research Use Only

Monoclonal

1H1

2 mg/ml

Unconjugated

NFIB

nuclear factor I B

CTF, HMGIC/NFIB, MACID, NF-I/B, NF1-B, NFI-B, NFI-RED, NFIB2, NFIB3, nuclear factor 1 B-type, CCAAT-box-binding transcription factor, TGGCA-binding protein, nuclear factor 1/B

Mouse

IgG2b

Nuclear factor 1 B-type

NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161